ThunderStorm™ System

Fully automated, high-throughput targeted sequencing system

The RainDance ThunderStorm™ System is a fully automated high-throughput targeted sequencing solution that enables researchers to process more samples per day and generate higher-quality data faster than ever before. The system features true walkaway capabilities that will automatically process up to 96 samples and access up to eight different primer panels. The ThunderStorm System leverages RainDance’s proven single molecule PCR technology that generates millions of unique microdroplet PCR reactions, enabling scientists to target up to 20,000 genomic loci in a single sample. The RainDance ThunderStorm System combines premium performance and a proven technology platform to deliver unprecedented daily sample throughput with the most attractive running economics and minimal hands-on time.

ThunderStorm System

Fully automated high-throughput targeted sequencing system 1 to 96 samples per run

Compatible with all NGS platforms
– Illumina’s HiSeq™ and MiSeq™
– Ion Torrent’s PGM™
– Life’s 5500 SOLiD™
– PacBio’s RS
– Roche’s GS FLX™ and GS Junior™ Systems

Broad range of applications: GWAS follow up, medical genetics, somatic mutation analysis, epigenetics

Low cost per sample: high-volume chips manufactured by Sony DADC, elimination of sequencing library costs

Highest quality data: proven RainDance sequence coverage and uniformity

ThunderStorm™ System Advantages

  • Comprehensive genomic coverage: Determine all variation contained in any desired region of the genome
  • Unparalleled target selection: Increased accuracy and greater coverage uniformity; requires less sequencing per sample than alternative enrichment methods
  • Production ready for clinical research lab: Enable high-throughput screening and validation for mutation analysis and interpretation for genetic disorders using next-generation sequencing
  • Reduced sample input requirements: Use as little as 250ng of unamplified genomic DNA
  • Elimination of downstream NGS library processing: Integrate sequencing adaptors directly into sequence-ready targets with RainDance’s Tailed Primer Assay
  • Fast turnaround and simple workflow: Generate sequence-ready samples in as little as 4 hours from sample to sequencer
  • Designed for the future: Enabled for amplicon sizes from 150bp - 1.5kb today and up to ~10 kb in the future