Our Technology
Applying simplicity and speed to solve complex
biological problems
RainDance Technologies’ (RDT) innovative RainStorm™ microdroplet-based technology is finding broad application in the prediction and prevention of human disease. This work includes application of our technology to proven assays such as PCR and cell sorting. The simplicity and speed of RainStorm technology will enable researchers to design experiments in ways that were previously unaffordable or unimaginable.
Our technology produces picoliter-volume droplets at a rate of 10 million per hour, avoiding unnecessarily complex automation solutions. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. The droplets are processed on a disposable chip that has no moving parts or valves. Samples have minimal contact with either walls or air. When our versatile technology is applied to highly-cited assays, we create high-speed workflows that minimize the process-induced bias or error commonly associated with multiplexed technologies. With its preparative and analytical capabilities, RainStorm technology is sufficiently flexible for a variety of applications using a simplified workflow integration of sample preparation, analysis, on-chip processing, and sample recovery for subsequent investigations.
RainStorm technology will find utility in numerous biomedical applications, including genomics research, gene expression analysis, compound screening, and biomarker detection. As the challenges in life sciences research become increasingly complex, straightforward solutions will simplify these problems and reduce them to their easiest-to-understand components. By combining the essential features of picoliter-sized droplets in which discrete reactions are created, single cells, beads, or molecules can be compartmentalized and processed for analysis.
Learn more about the RainStorm difference.
See examples of RainStorm technology in action:
(High-speed videos have been slowed down by a factor of 1,000 to visualize individual droplets. The droplets are flowing at the rate of 3,000 per second.)

